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The crystal composition of the ligelizumab svFv:IgE-Fc3-four intricate gives in-depth insights into its power to inhibit FcεRI and CD23 binding (Fig. 2g–k). Views on the IgE:ligelizumab and IgE:FcεRIα complexes along the IgE dimer axis show the two ligelizumab scFvs mimic the preparations of FcεRI and IgE Cεtwo domains on both aspect of you